Breast and Colon Cancer Family Registries
For Research Collaborators: Biospecimens
The Breast and Colon Cancer Family Registries (CFR) collect biospecimens from registry participants and provide access to collaborative scientists for research purposes. These biospecimens are a precious resource and applications for their use are examined by the BC-CFR. Potential collaborators of the BC-CFR are asked to consider this when requesting quantities and types of biospecimens.
The following types of biospecimens are available from all sites (pending approval):
- Lymphocyte DNA, participants affected and unaffected with cancer
- DNA from established cell lines from probands affected and unaffected with cancer
- Cell lines established, probands affected and unaffected with cancer
- Plasma, participants affected and unaffected with cancer
- DNA, tumor tissue and normal tissue
- Tissue, tumor and normal
- Granulocytes, participants affected and unaffected with cancer
- Blood spots on Guthrie cards from affected and unaffected with cancer
- Slides from paraffin blocks
- Sections from paraffin blocks
The following types are available from selected sites (pending approval):
- DNA from buccal swabs/swish
- DNA from granulocytes
- DNA from Guthrie spots (Australia B-CFR only)
- Urine specimen (New York Center B-CFR only)
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The CFR biospecimen repository policies and procedures were evaluated
by The RAND Corporation and were included in a best practices review. Case Studies of Existing Human Tissue Repositories  "Best Practices" for a Biospecimen Resource for the Genomic and Proteomic Era Elisa Eiseman, Gabrielle Bloom, Jennifer Brower, Noreen Clancy and Stuart Olmsted |
For more information on acquiring biospecimens once the application is approved, please see the Biospecimen Costs (PDF) and Material Transfer Agreement (PDF) forms.
