Breast and Colon Cancer Family Registries
About Breast CFR
The Breast Cancer Family Registry (B-CFR) is an international research infrastructure for investigators interested in conducting population and clinic-based interdisciplinary studies on the genetic and molecular epidemiology of breast cancer and its behavioral implications. A central goal of the B-CFR is the translation of this research to the clinical and prevention setting for the benefit of Registry participants and the general public. The B-CFR has information and biospecimens contributed by more than 12,500 families across the spectrum of risk for these cancers and from population-based or relative controls.
Of particular interest are:
- identification and characterization of cancer susceptibility genes
- definition of gene-gene and gene-environment interactions in cancer etiology
- translational, preventive, and behavioral implications of research findings
Special features include:
- population-based and clinic-based ascertainment
- systematic collection of validated family history
- epidemiologic risk factor data
- clinical and follow-up data
- biospecimens (including tumor blocks and EBV-transformed cell lines)
- ongoing molecular characterization of the participating families
